Tobacco smoking and colorectal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population.

High colorectal cancer risk is associated with tobacco smoking.

This study investigated the effect of tobacco smoking on colorectal cancer risk among Japanese men and women. Researchers reviewed data obtained from 6 cohort and 15 case-control studies that examined tobacco smoking as a risk factor for colorectal cancer.

Researchers observed that tobacco smokers had high risk of developing colon, rectal, and colorectal cancer. The findings of this meta-analysis show that tobacco smoking may contribute positively to the development of colorectal cancer.