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Antidepressant Use and Risk of Epilepsy and Seizures in People Aged 20 to 64 Years: Cohort Study Using a Primary Care Database
The use of antidepressants is tied to higher risk of seizure and epilepsy.
This study was conducted to assess whether people who take antidepressants are at increased risk of developing seizure and epilepsy. Researchers monitored the drug prescription of 283,963 patients with depression aged 20-64 years. During the 5-year study period, 878 patients had experienced their first episode of seizure.
Researchers discovered that the incidence of seizure and epilepsy rose with the use of antidepressant medications. This study points out that antidepressant use might be a risk factor for the development of seizure and epilepsy.
Research Summary Information
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2015
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Trevor Hill , Carol Coupland , Richard Morriss , Antony Arthur , Michael Moore , Julia Hippisley-Cox
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Division of Primary Care, University of Nottingham, 13th floor, Tower Building, University Park, Nottingham, NG7 2RD, UK. T.Hill@nottingham.ac.uk. Division of Primary Care, University of Nottingham, 13th floor, Tower Building, University Park, Nottingham, NG7 2RD, UK. Carol.Coupland@nottingham.ac.uk. Institute of Mental Health, Jubilee Campus, University of Nottingham Innovation Park, Triumph Road, Nottingham, NG7 2TU, UK. Richard.Morriss@nottingham.ac.uk. School of Health Sciences, Faculty of Medicine and Health Sciences, Edith Cavell Building, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. Antony.Arthur@uea.ac.uk. University of Southampton Faculty of Medicine, Primary Care and Population Sciences, Aldermoor Health Centre, Aldermoor Close, Southampton, SO16 5ST, UK. mvm198@soton.ac.uk. Division of Primary Care, University of Nottingham, 13th floor, Tower Building, University Park, Nottingham, NG7 2RD, UK. juliahippisleycox@gmail.com.
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Yes, Free full text of study was found:
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