Dietary caffeine intake and the risk for detrusor instability: a case-control study.

Frequent intake of generous amounts of caffeine-containing foods and drinks may be a risk factor for detrusor instability in women.

​Detrusor instability, also known as unstable bladder, is a medical condition in which spontaneous and uninhibited contraction of the detrusor muscle (a smooth muscle found in the wall of the urinary bladder that facilitates its relaxation to allow for filling and storage of urine and contraction of the bladder during urination in order to push urine to the urethra) occurs during bladder filling, resulting in urinary incontinence and sometimes recurrent urinary tract infection. 

This study looked at the correlation between dietary ingestion of caffeine and the occurrence of detrusor instability. Researchers examined the caffeine consumption rate of 131 women with detrusor instability and 128 females without detrusor instability. The team of investigators found a high prevalence of detrusor instability among high consumers of caffeine-containing foods and drinks. This study provides strong evidence that women on high caffeine diet may be highly prone to suffer from detrusor instability.