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Proinflammatory Diet Increases the Risk of Irritable Bowel Syndrome: A Prospective Study of 129,408 UK Biobank Participants and Mendelian Randomization Analysis

Sticking to a proinflammatory diet may fuel the development of irritable bowel syndrome (IBS).

This study evaluated the link between eating a proinflammatory diet and the odds of developing irritable bowel syndrome (IBS). The study included 129,408 UK men and women who provided dietary and health information via questionnaires. 

Researchers discovered that high dietary intake of proinflammatory foods correlated with heightened risk of irritable bowel syndrome. This study provided robust evidence that promoting the consumption of proinflammatory diets may result in an upsurge in the incidence of irritable bowel syndrome in men and women.

Research Summary Information

  • 2024
  • Laifu Li, Yan Ran, Yan Zhuang, Ying Xu, Lianli Wang, Lele Chen, Yating Sun, Fangchen Ye, Lin Mei, Fei Dai
  • Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. Shaanxi Province Key Laboratory of Gastrointestinal Motility Disorders, Xi'an, China. Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China. Department of Vascular Surgery, Xincai County People's Hospital, Xincai, China. Department of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. daifei68@xjtu.edu.cn. Shaanxi Province Key Laboratory of Gastrointestinal Motility Disorders, Xi'an, China. daifei68@xjtu.edu.cn.
  • No, Free full text of study was not found.
    
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