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Vascular events in healthy older women receiving calcium supplementation: randomized controlled trial.
The intake of calcium supplements is linked with high risk of stroke, angina, myocardial infarction, ischemic heart attack, and sudden death.
This study was carried out to determine the effect of calcium supplements on cardiovascular events, such as stroke, myocardial infarction, and sudden death. Researchers administered calcium supplements to 732 women and placebo to another group of 739 females, all post-menopausal. The stroke, angina, myocardial infarction, ischemic heart attack, and total mortality risks were assessed in all the subjects.
Researchers observed a higher incidence of myocardial infarction in the calcium group than in the placebo group. Increased stroke, angina, ischemic heart attack, and total mortality risks were also found in subjects given calcium supplements. The findings of this study show that the intake of calcium supplements is associated with the occurrence of adverse cardiovascular events, such as stroke, angina, myocardial infarction, ischemic heart attack, and sudden death.
Research Summary Information
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2008
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Bolland MJ, Barber PA, Doughty RN, Mason B, Horne A, Ames R, Gamble GD, Grey A, Reid IR.
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Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
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Yes, Free full text of study was found:
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Yes. Source of funding disclosure found
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This study was supported by the Health Research Council of New Zealand. Mission Pharmacal supplied the calcium citrate tablets and placebo.
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Yes. Potential conflicts disclosure found
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IRR has received research support from and acted as a consultant for Fonterra and Mission Pharmacal.
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