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Dietary fat and postmenopausal invasive breast cancer in the National Institutes of Health-AARP Diet and Health Study cohort.

​Postmenopausal women on high-fat diets may have a high tendency of developing invasive breast cancer.

This study investigated whether an association exists between dietary fat intake and invasive breast cancer risk in postmenopausal women. Using a validated 124-item food frequency questionnaire, researchers collated and analyzed data on the fat intake of 188,736 postmenopausal US women recruited from the National Institutes of Health-AARP Diet and Health Study. The breast cancer hazard ratios of the participants in this study were also ascertained.

Researchers observed that postmenopausal women who consumed the most fatty foods had higher risk of developing invasive breast cancer than women on low-fat diets. Data from this study support the hypothesis that high intake of dietary fat is positively associated with elevated breast cancer risk in postmenopausal women.

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