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Associations of dietary isothiocyanate exposure from cruciferous vegetable consumption with recurrence and progression of non-muscle-invasive bladder cancer: findings from the Be-Well Study
Eating isothiocyanate-rich foods, such as cruciferous vegetables, may help halt the spread and re-occurrence of bladder cancer in men and women.
The purpose of this study was to clarify the relationship between high dietary exposure to isothiocyanates from cruciferous vegetables and the risk of progression and recurrence of bladder cancer. With the aid of validated food frequency questionnaires, researchers collated and analyzed information on the dietary choices of 1,143 persons diagnosed with bladder cancer over a 25-month period. During the course of the study, 30% of the participants had recurrence of bladder cancer and 6.7% experienced disease progression.
Researchers noted that frequent consumers of isothiocyanates from cruciferous vegetables constitute a small proportion of the participants that suffered from worsening and recurrence of bladder cancer. This study highlighted the role cruciferous vegetables play in reducing the risk of disease progression and recurrence in patients with bladder cancer.
Research Summary Information
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2023
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Zinian Wang, Marilyn L Kwan, Reina Haque, Maciej Goniewicz, Rachel Pratt, Valerie S Lee, Janise M Roh, Isaac J Ergas, Kimberly L Cannavale, Ronald K Loo, David S Aaronson, Charles P Quesenberry, Yuesheng Zhang, Christine B Ambrosone, Lawrence H Kushi, Li Tang
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Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States. Division of Research, Kaiser Permanente Northern California, Oakland, CA, United States. Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, United States; Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA, United States. Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States. Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, United States. Department of Urology, Kaiser Permanente Downey Medical Center, Downey, CA, United States. Department of Urology, Kaiser Permanente Oakland Medical Center, Oakland, CA, United States. Department of Pharmacology and Toxicology, and Massey Cancer Center, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States. Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States. Electronic address: li.tang@roswellpark.org.
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No, Free full text of study was not found.
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