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Research Summaries

Research Team that works on the Science Health Research Summaries and other research projects.

Vascular events in healthy older women receiving calcium supplementation: randomized controlled trial.

March 14, 2016

Research Summaries

Cardiovascular Disease Stroke Cardiovascular Vascular Supplements

The intake of calcium supplements is linked with high risk of stroke, angina, myocardial infarction, ischemic heart attack, and sudden death.

Research Summary Information

INFORMATION
Year
2008
Author
Bolland MJ, Barber PA, Doughty RN, Mason B, Horne A, Ames R, Gamble GD, Grey A, Reid IR.
Credit
Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
BMJ Full Text Publication
DISCLOSURES
Funding?
Yes. Source of funding disclosure found
Funding Note
This study was supported by the Health Research Council of New Zealand. Mission Pharmacal supplied the calcium citrate tablets and placebo.
Conflicts?
Yes. Potential conflicts disclosure found
Conflict Note
IRR has received research support from and acted as a consultant for Fonterra and Mission Pharmacal.

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Calcium suppplement and cardiovascular risk: 5 years on.

March 11, 2016

Research Summaries

Cardiovascular Disease Stroke Cardiovascular Vascular Supplements

High intake of calcium supplements may promote the development of adverse cardiovascular events, such as stroke and myocardial infarction.

Research Summary Information

INFORMATION
Year
2013
Author
Mark J. Bolland, Andrew Grey, and Ian R. Reid
Credit
Mark J. Bolland, Bone and Joint Research Group, Department of Medicine, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed Full Text Publication
Link #2:
Sage Journals Abstract
Link #3:
Sage Journals PDF Version of Full Text Publication
DISCLOSURES
Funding?
Yes. Source of funding disclosure found
Funding Note
This work was supported by the Health Research Council of New Zealand and the University of Auckland School of Medicine Foundation. MB is the recipient of a Sir Charles Hercus Health Research Fellowship.
Conflicts?
No. Potential conflicts disclosure not found

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Cardiovascular Stroke Myocardial Infarction Dietary Calcium Calcium Supplements

Mechanism of free fatty acid induced insulin resistance in humans.

March 8, 2016

Research Summaries

Type 2 Diabetes High Triglycerides Insulin Resistance

The inhibitory action of free fatty acids on glucose transport, oxidation, and glycogen synthesis may be responsible for lipid-induced insulin resistance in humans.

Research Summary Information

INFORMATION
Year
1996
Author
M Roden, T B Price, G Perseghin, K F Petersen, D L Rothman, G W Cline, G I Shulman
Credit
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed PDF Version of Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
The Journal Clinical Investigation Abstract
DISCLOSURES

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Fatty Acids Insulin Resistance Glucose Uptake Diabetes Mellitus Glycogen Synthesis

Cholesterol crystals cause mechanical damage to biological membranes: a proposed mechanism of plaque rupture and erosion leading to arterial thrombosis.

March 6, 2016

Research Summaries

Atherosclerosis Arterial Thrombosis Artery Total Cholesterol

Cholesterol crystals may promote arterial thrombosis via arteriosclerotic plaque disruption and erosion.

Research Summary Information

INFORMATION
Year
2005
Author
Abela GS, Aziz K.
Credit
Department of Medicine, Division of Cardiology, Michigan State University, East Lansing, Michigan 48824 , USA. george.abela@ht.msu.edu
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
Clinical Cardiology PDF Version of Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
Wiley Online Library Abstract
DISCLOSURES
Funding?
Yes. Source of funding disclosure found
Funding Note
Michigan State University. Grant Number: IRGP147 National Institutes of Health. Grant Number: R01:HL067472
Conflicts?
No. Potential conflicts disclosure not found

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Plaque Disruption Cholesterol Atherosclerosis Cardiovascular

Comparison of nutrient density and nutrient-to-cost between cooked and canned beans.

March 3, 2016

Research Summaries

Beans & Legumes

Cooked beans contain more nutrients than canned beans.

Research Summary Information

INFORMATION
Year
2011
Author
Michael Zanovec, Carol E. O’Neil, Theresa A. Nicklas
Credit
School of Human Ecology, Louisiana State University Agricultural Center, Baton Rouge, LA, USA; 2USDA/ARS Children’s Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA. E-mail: coneil1@lsu.edu
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
Scientific Research PDF Version of Full Text Publication
Link #2:
Scientific Research Abstract
Link #3:
ResearchGate Abstract
DISCLOSURES

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Canned Beans Cooked Beans Protein Fiber

The nutritional and health benefits of pulses in relation to obesity, diabetes, heart disease, and cancer.

March 2, 2016

Research Summaries

Cancer Type 2 Diabetes Obesity Vascular Beans & Legumes

Eating large quantities of pulses may lower the cancer, obesity, diabetes, and heart disease risk.

Research Summary Information

INFORMATION
Year
2012
Author
Curran J
Credit
Scientific and Regulatory Affairs, Pulse Canada, 1212-220 Portage Avenue, Winnipeg, Manitoba, Canada R3C 0A5. jcurran@pulsecanada.com
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
British Journal of Nutrition PDF Version of Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
ResearchGate Abstract
DISCLOSURES

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Pulses Cancer Obesity Diabetes Heart Disease

Cholesterol crystals and inflammation.

March 1, 2016

Research Summaries

Cardiovascular Disease Vascular Artery Cholesterol

High serum concentrations of cholesterol crystals may elevate vascular inflammation in cardiovascular ailments and atherosclerosis risk.

Research Summary Information

INFORMATION
Year
2011
Author
Grebe A, Latz E.
Credit
Institute of Innate Immunity, University Hospitals Bonn, Bonn, Germany. alena.grebe@uni-bonn.de
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
Current Rheumatology Reports Full Text Publication
DISCLOSURES

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Cholesterol Atherosclerosis Vascular Inflammation

Dietary cholesterol and egg yolk: not for patients at risk of vascular disease.

February 29, 2016

Research Summaries

Cardiovascular Disease Vascular Eggs

High consumption of dietary cholesterol promotes the development of vascular diseases.

Research Summary Information

INFORMATION
Year
2010
Author
Spence JD, Jenkins DJ, Davignon J.
Credit
Stroke Prevention & Atherosclerosis Research Centre, Robarts Research Institute, London; Risk Factor Modification Centre, St Michael’s Hospital, Toronto, Ontario; Clinique de nutrition métabolisme et athérosclérose, Institut de recherches cliniques de Montréal, Montreal, Quebec
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
ScienceDirect Full Text Publication
DISCLOSURES

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Cholesterol Egg Yolk Cardiovascular

Acute blood pressure lowering, vasoprotective,and antiplatelet properties of dietary nitrate via bioconversion to nitrite.

February 29, 2016

Research Summaries

Cardiovascular Disease Vascular Endothelial Cells Carotenoids Fruits Vegetables

Nitrate-rich fruits and vegetables may lower high blood pressure and reduce cardiovascular disease risk.

Research Summary Information

INFORMATION
Year
2008
Author
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ, Ahluwalia A.
Credit
Clinical Pharmacology, William Harvey Research Institute, Barts & the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
Hypertension Full Text Publication
DISCLOSURES

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Fruit Vegetables Cardiovascular Endothelial Function Blood Pressure

Optimal diets for prevention of coronary heart disease.

February 28, 2016

Research Summaries

Cardiovascular Disease Vascular Heart Exercise Fruits Nuts Vegetables Whole Grains

High intakes of fruits, nuts, vegetables, whole grains, unsaturated fats, and omega-3-fatty acids are associated with decreased coronary heart disease risk.

Research Summary Information

INFORMATION
Year
2002
Author
Hu FB, Willett WC.
Credit
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA. frank.hu@channing.harvard.edu
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
JAMA Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
JAMA Abstract
DISCLOSURES

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Fruit Vegetables Nuts Body Weight Heart Disease

Milk, dietary calcium, and bone fractures in women: a 12-year prospective study.

February 26, 2016

Research Summaries

Skeletal Bone Dairy Milk

Milk and other calcium-rich foods are not associated with lower risk of bone fractures in adult females.

Research Summary Information

INFORMATION
Year
1997
Author
Feskanich D, Willett WC, Stampfer MJ, Colditz GA.
Credit
Channing Laboratory, Boston, Mass. 02115, USA.
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed PDF Version of Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
The American Journal of Public Health PDF Version of Full Text Publication
DISCLOSURES
Funding?
Yes. Source of funding disclosure found
Funding Note
This study was supported by research grants AR 41383 and CA 40356 from the National Institutes of Health and by the US Department of Agriculture, Agricultural Research Service, under contract 533K06-5-10.
Conflicts?
No. Potential conflicts disclosure not found

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Milk Calcium Bone Fracture

Fish odour syndrome.

February 24, 2016

Research Summaries

Metabolic Disoders

Consuming large quantities of choline-rich foods may exacerbate fish odour syndrome.

Research Summary Information

INFORMATION
Year
1999
Author
H Rehman
Credit
Department of Medicine, Hull Royal Infirmary, UK.
AVAILABILITY
Available Free?
Yes, Free full text of study was found:
Link #1:
NCBI PubMed PDF Version of Full Text Publication
Link #2:
NCBI PubMed Abstract
Link #3:
BMJ Full Text Publication
DISCLOSURES

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Choline Carnitine Trimethylanimuria Fish Odour

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DrCarney.com Blog

The intake of calcium supplements is linked with high risk of stroke, angina, myocardial infarction, ischemic heart attack, and sudden death.

Research Summary Information

High intake of calcium supplements may promote the development of adverse cardiovascular events, such as stroke and myocardial infarction.

Research Summary Information

The inhibitory action of free fatty acids on glucose transport, oxidation, and glycogen synthesis may be responsible for lipid-induced insulin resistance in humans.

Research Summary Information

Cholesterol crystals may promote arterial thrombosis via arteriosclerotic plaque disruption and erosion.

Research Summary Information

Cooked beans contain more nutrients than canned beans.

Research Summary Information

Eating large quantities of pulses may lower the cancer, obesity, diabetes, and heart disease risk.

Research Summary Information

High serum concentrations of cholesterol crystals may elevate vascular inflammation in cardiovascular ailments and atherosclerosis risk.

Research Summary Information

High consumption of dietary cholesterol promotes the development of vascular diseases.

Research Summary Information

Nitrate-rich fruits and vegetables may lower high blood pressure and reduce cardiovascular disease risk.

Research Summary Information

High intakes of fruits, nuts, vegetables, whole grains, unsaturated fats, and omega-3-fatty acids are associated with decreased coronary heart disease risk.

Research Summary Information

Milk and other calcium-rich foods are not associated with lower risk of bone fractures in adult females.

Research Summary Information

Consuming large quantities of choline-rich foods may exacerbate fish odour syndrome.

Research Summary Information

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